Melbourne is know for its multicultural image and labyrinth of laneways, so when visiting Melbourne, it can be a bit of a task to decide which laneways to explore. To make this a bit easier, I tend to think "If someone had an hour to spare in Melbourne CBD and wanted something to do, what would I suggest?" The answer to this, would likely be directing them to the main Laneway that gets mentioned by most people, that place is Hosier Lane and it's a fantastic starting block to place yourself when wanting to explore the remaining CBD.
Hosier Lane is filled with various forms of art work pasted all along its walls at various hights and angles, plus you don't have to be an "arty type" to appreciate the detail and imagination of each art piece. The laneway is opposite Federation Square and very close to Degraves Street, which is another popular laneway for when in need of a caffeine hit or a bit of food.
Surrounding Hosier lane are even more laneways with various quirks to them, but Hosier Lane is the central hub of street art that showcases the best of Melbourne street art.